Characteristics of COVID-19 Vaccines Available in Canada

Pfizer-BioNTech Moderna
Vaccine Technology mRNA mRNA
Packaging

Multi-dose preservative-free vials containing 5 doses

Cartons of 25 and 195 vials

Multi-dose preservative-free vials containing 10 doses

Cartons of 10 vials

Storage/Stability
Freezer Store at -80°C to -60°C (ultrafreezer) Store at -25°C to -15°C (freezer) 
Stability in Fridge (2°C to 8°C) Undiluted product: up to 5 days Up to 30 days
Thawing
(Do not refreeze)
Thaw undiluted product in fridge (takes up to 3 hours)
or
Thaw undiluted product at room temperature (takes ~30 minutes)  
Thaw in fridge (takes 2.5 hours), let stand at room temperature for 15 minutes before administration
or
Thaw at room temperature (takes 1 hour)
Dilution

Dilute thawed vials once they have reached room temperature with 1.8 mL of sterile 0.9% Sodium Chloride
Injection, USP

Dilution not required
Stability at Room Temperature (up to 25°C) Prior to dilution, no more than 2 hours
After dilution, use within 6 hours from time of dilution
Up to 12 hours 
Stability after 1st puncture Up to 6 hours Up to 6 hours 
Stability in predrawn syringe
Note: predraw as few as possible
Up to 6 hours (if other stability parameters are met) Up to 6 hours (if other stability parameters are met)
Clinical Information
Age Approved for those 16 years and older
(Limited data for those 12-15 years)
Approved for those 18 years and older
Dose 2x 0.3 ml doses
21-28 days* apart
Minimum interval = 19 days
2x 0.5 ml doses
28 days* apart
Minimum interval = 21 days
Route of Administration Intramuscular (deltoid) Intramuscular (deltoid)
*Up to 42 days if needed in times of vaccine supply constraint.