The medSask newsletter is a monthly publication curated for pharmacists in Saskatchewan. Through our newsletter, we highlight information and resources to support pharmacists through practice changes, minor ailment prescribing, and drug shortages. The newsletter also includes frequently asked questions we receive through our health care professional line.
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Recent Editions

January 30, 2024: RSV Vaccine Update, Drug shortages, Sublocade®
December 26, 2023: Respiratory Virus  Updates, Ozempic, New Minor Ailments

January 30, 2024: RSV Vaccine Update, Drug shortages, Sublocade®

Read Now

https://mailchi.mp/usask.ca/medsask-newsletter-january-30-2024?e=[UNIQID] 

Summary/Highlights
References

RSV Vaccines

  1. Arexvy. Product Monograph. GlaxoSmithKline Inc.; 2023. Accessed 22 Jan 2024. https://pdf.hres.ca/dpd_pm/00071904.PDF
  2. Abrysvo. Product Monograph. Pfizer Canada; 2023. Accessed 22 Jan 2024. https://pdf.hres.ca/dpd_pm/00073900.PDF
  3. Preventing RSV. Pharmacists’s Letter. Therapeutic Research Center. October 2023. Accessed 19 Jan 2024. https://pharmacist.therapeuticresearch.com/Content/Segments/PRL/2023/Oct/Preventing-RSV-S2310001
  4. Papi A, Ison MG, Langley JM, Lee DG, Leroux-Roels I, Martinon-Torres F, Schwarz TF, van Zyl-Smit RN, Campora L, Dezutter N, de Schrevel N. Respiratory syncytial virus prefusion F protein vaccine in older adults. New England Journal of Medicine. 2023 Feb 16;388(7):595-608.
  5. Walsh EE, Pérez Marc G, Zareba AM, Falsey AR, Jiang Q, Patton M, Polack FP, Llapur C, Doreski PA, Ilangovan K, Rämet M. Efficacy and safety of a bivalent RSV prefusion F vaccine in older adults. New England Journal of Medicine. 2023 Apr 20;388(16):1465-77.

AEFIs

  1. Administration of Drugs by Injection and Other Routes Guidelines. Saskatchewan College of Pharmacy Professionals. June 27, 2023. Accessed January 18, 2024. https://saskpharm.ca/document/3614/REF_Injection_Admin_Gdlns_20171213.pdf
  2. Saskatchewan User Guide for Completion and Submission of Adverse Events Following Immunization (AEFI) Reports. Government of Saskatchewan. December 2021. Accessed January 18, 2024. https://www.ehealthsask.ca/services/Manuals/Documents/SK%20AEFI%20User%20Guide.pdf

Hepatitis A Vaccine Shortage

  1. Search products. Drug Shortages Canada. 2024. Accessed January 17, 2024. https://www.drugshortagescanada.ca/drugsearch?perform=0
  2. McKesson Canada. PharmaClik. 2024. Accessed January 17, 2024. http://clients.mckesson.ca

Glucagon Shortage

  1. Risk communication letter. Amphastar. June 28, 2023. Accessed January 24, 2024. https://medsask.usask.ca/sites/medsask/files/2024-01/risk-communication-letter-glucagon-EN.pdf
  2. Drug Plan and Extended Benefits. Drug shortages: glucagon injection. Saskatchewan Ministry of Health. January 19, 2024. Accessed January 24, 2024. https://medsask.usask.ca/sites/medsask/files/2024-01/dpeb-874-US-labelled-glucagon-for-injection.pdf 

Nicotine Pouches Arrive in Canada

  1. Quit with confidence: how to quit. Health Canada. Updated November 9, 2023. Accessed January 16, 2024. https://www.canada.ca/en/health-canada/services/smoking-tobacco/quit-smoking/how.html
  2. Licensed Natural Health Products Database. Health Canada; 2023. Accessed January 16, 2024. https://health-products.canada.ca/lnhpd-bdpsnh/info?licence=80125630
  3. LungSask. Health Canada approves BAT's Zonnic non-tobacco nicotine pouch for sale in Canada. July 24, 2023. Accessed January 16, 2024. https://www.lungsask.ca/news/2023-07/health-canada-approves-bats-zonnic-non-tobacco-nicotine-pouch-sale-canada
  4. CCS. Health Canada makes it legal for flavoured nicotine products from Imperial Tobacco to be sold to children. Canadian Cancer Society. November 14, 2023. Accessed January 16, 2024. https://cancer.ca/en/about-us/media-releases/2023/nicotine-pouches-legal-for-children
  5. Patwardhan S, Fagerström K. The new nicotine pouch category: a tobacco harm reduction tool? Nicotine Tob Res. 2022;24(4):623–625. doi: 10.1093/ntr/ntab198.
  6. Sawin S. Nicotine cessation. medSask. Updated December 4, 2023. Accessed January 17, 2024. https://medsask-usask-ca.cyber.usask.ca/minor-ailment-guidelines-Saskatchewan/nicotine-cessation 

Sublocade

  1. Sublocade. Product Monograph. Indivior UK Limited; 2022. Accessed Jan 23, 2024. https://pdf.hres.ca/dpd_pm/00066524.PDF  
  2. Saskatchewan College of Pharmacy Professionals. Opioid Agonist Therapy (OAT) Standards. Revised Oct 2020. Accessed Jan 23, 2024. https://www.saskpharm.ca/document/5871/REF_OAT_Standards.pdf   
  3. BCCSU. Sublocade (Extended-Release Buprenorphine) Information. Updated Jan 11, 2022. Accessed Jan 23, 2024. https://www.bccsu.ca/wp-content/uploads/2022/01/Bulletin-Sublocade-Jan2022.pdf   
  4. Wiebe A, Regier L. Opioid Analgesics. RxFiles. University of Saskatchewan. July 2023. Accessed Jan 23, 2024. https://www-rxfiles-ca.cyber.usask.ca/RxFiles/uploads/documents/members/CHT-Opioid.pdf    
  5. Wiebe A, Crawley A, Bareham J. Treating Opioid Use Disorder In Primary Care. RxFiles. University of Saskatchewan. Spring/Summer 2021 Newsletter. Accessed Jan 24, 2024. https://www-rxfiles-ca.cyber.usask.ca/RxFiles/uploads/documents/members/newsletter-OAT.pdf
  6. Saskatchewan College of Pharmacy Professionals. SCOPe newsletter. June 2020. Accessed Jan 24, 2024. https://saskpharm.ca/document/6108/SCOPe_Vol_12_2_June_2020.pdf
  7. Phone correspondence with Matt Manz, BSP. 306-522-5300 Jan 17th, 2024.
  8. AIMS Presentation 2023. Beyond Dispensing: The Role of the Pharmacist in Opioid Agonist Therapy. Internal document.

Delayed Vaccine Doses

  1. Timing of vaccine administration: Canadian Immunization Guide. Public Health Agency of Canada. Updated November 2017. Accessed January 24, 2024. https://www.canada.ca/en/public-health/services/canadian-immunization-guide/updates.html#t2015
  2. Zerbo O, Bartlett J, Fireman B, et al. Effectiveness of recombinant zoster vaccine against herpes zoster in a real-world setting. Ann Intern Med. Published online January 9, 2024. (accessed January 16, 2024).

December 26, 2023: Respiratory Virus Updates, Ozempic, New Minor Ailments

Read Now

https://mailchi.mp/usask.ca/medsask-newsletter-december-26-2023?e=[UNIQID] 

Summary/Highlights
  • Respiratory Virus Season
    • Remind people about influenza vaccines
    • Vaccination following infection
    • Novavax Nuvaxovid XBB.1.5
    • The Cold Standard
  • Drug Shortages
    • Ozempic®
    • Cephalexin oral suspension
    • Levodopa/carbidopa CR
    • Verapamil SR
  • Minor Ailments
    • New conditions: nausea and vomiting of pregnancy, recurrent genital herpes
  • Professional Practice
    • Newest kid on the diabetes block – Mounjaro®
    • Cranberries aren’t just for turkey dinners…
  • From the medSask Database
    • Prolia® FAQs
    • Jen’s resource share – Deprescribing.org
  • Share your feedback with medSask! Help us create a valuable newsletter each month by completing a short (2-minute) survey.
References

Respiratory Virus Season 

  1. Community Respiratory Illness Surveillance Program Situation Report: December 08, 2023 (Reporting Period November 19 –December 02, 2023). Accessed December 18, 2023. https://www.saskatchewan.ca/government/health-care-administration-and-provider-resources/treatment-procedures-and-guidelines/emerging-public-health-issues/2019-novel-coronavirus/cases-and-risk-of-covid-19-in-saskatchewan 
  2. Saskatchewan Immunization Manual. COVID-19 Vaccine Q &A for Immunizers. Updated December 2023. Accessed December 18, 2023. https://www.ehealthsask.ca/services/Manuals/Documents/Ch.%2010%20Biological%20Products.pdf 
  3. Centers for Disease Control and Prevention. RSV Vaccination for Older Adults 60 Years of Age and Over. Updated August 30, 2023, Accessed December 18, 2023. https://www.cdc.gov/vaccines/vpd/rsv/public/older-adults.html#:~:text=There%20is%20no%20specific%20length,can%20get%20an%20RSV%20vaccine. 
  4. Respiratory syncytial virus (RSV). Canadian Immunization Guide. Government of Canada. Updated September 8, 2023. Accessed October 18, 2023. https://www.canada.ca/en/public-health/services/publications/healthy-living/canadian-immunization-guide-part-4-active-vaccines/respiratory-syncytial-virus.html#a3 
  5. Vaccines and Related Biological Products Advisory Committee Meeting Materials. RSV Immunity, Durability, and Reinfection. Accessed December 18, 2023. https://www.fda.gov/media/165733/download 
  6. Immunize.org. Ask the Experts: Influenza. Updated September 10, 2023. Accessed December 18, 2023. https://www.immunize.org/ask-experts/topic/influenza/page/2/ 
  7. Saskatchewan Ministry of Health. COVID-19 program updates: Novavax Nuvaxovid™ XBB.1.5 vaccine for 12+ years. COVID-19 Immunization Manual. December 12, 2023. Accessed December 17, 2023. https://www.ehealthsask.ca/services/Manuals/Documents/COVID-19%20Updates%20-%20Novavax%20XBB.1.5-Schedules%20updated%202023-12-12.pdf 

Minor Ailments 

  1. Norfield J. Nausea and vomiting of pregnancy (mild). medSask; 2023 [cited 2023 Dec 15]. https://medsask.usask.ca/nausea-and-vomiting-of-pregnancy 
  2. Boechler K. Recurrent genital herpes. medSask; 2023 [cited 2023 Dec 15]. https://medsask.usask.ca/recurrent-genital-herpes 

Mounjaro 

  1. Drug product database online query. Health Canada. 2023. Accessed December 13, 2023. https://health-products.canada.ca/dpd-bdpp/ 
  2. Mounjaro. Product Monograph. Eli Lilly Canada Inc.; 2023. Accessed December 17, 2023. https://pdf.hres.ca/dpd_pm/00072280.PDF 
  3. McKesson Canada. PharmaClik. 2023. Accessed December 13, 2023. http://clients.mckesson.ca 
  4. Vadher K, Patel H, Mody R, et al. Efficacy of tirzepatide 5, 10 and 15mg versus semaglutide 2 mg in patients with type 2 diabetes: an adjusted indirect treatment comparison. Diabetes Obes Metab. 2022 Sep;24(9):1861-1868. doi: 10.1111/dom.14775 
  5. Nicholls SJ, Bhatt DL, Buse JB, et al; SURPASS-CVOT investigators. Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes and atherosclerotic cardiovascular disease: SURPASS-CVOT design and baseline characteristics. Am Heart J. 2023 Sep 25; 267:1-11. doi: 10.1016/j.ahj.2023.09.007   
  6. ClinicalTrials.gov. A Study of tirzepatide (LY3298176) in participants with overweight or obesity and chronic kidney disease with or without type 2 diabetes (TREASURE-CKD). National Library of Medicine. Updated October 17, 2023. Accessed November 19, 2023. https://clinicaltrials.gov/study/NCT05536804 
  7. Saskatchewan Drug Plan. Home – search formulary. Government of Saskatchewan: Drug Plan and Extended Benefits Branch. 2023. Accessed December 17, 2023. https://formulary.drugplan.ehealthsask.ca/SearchFormulary 
  8. Express Scripts. Drug benefit list. Non-Insured Health Benefits. 2023. Accessed December 17, 2023. https://nihb-ssna.express-scripts.ca/en/0205140506092019/16/160407 
  9. Zepbound. Prescribing information. Eli Lilly and Company; 2023. Accessed December 15, 2023.  https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/217806s000lbl.pdf  

Cranberry for UTI 

  1. Williams G, Stothart CI, Hahn D, Stephens JH, Craig JC, Hodson EM. Cranberries for preventing urinary tract infections. Cochrane Database Syst Rev. 2023 Nov 10;11(11):CD001321. doi: 10.1002/14651858.CD001321.pub7. PMID: 37947276; PMCID: PMC10636779. 
  2. McClung S, LeBras M. Urinary Tract infections (UTIs). RxFiles. University of Saskatchewan. July 2023. Accessed Dec 12, 2023. https://www-rxfiles-ca.cyber.usask.ca/RxFiles/uploads/documents/members/CHT-UTI-Tx.pdf   
  3. Cranberry. In: NatMedPro. Therapeutic Research Center. Updated Sept 1, 2023. Accessed Dec 12, 2023. https://naturalmedicines-therapeuticresearch-com.cyber.usask.ca/databases/food,-herbs-supplements/professional.aspx?productid=958   
  4. Nicolle L. Urinary Tract Infections. CPS. Canadian Pharmacist’s Association. Updated Sept 28, 2023. Accessed Dec 12, 2023. https://www-e-therapeutics-ca.cyber.usask.ca/print/new/documents/CHAPTER/en/urinary_tract_infection   
  5. ACOG. Urinary Tract Infections (UTI’s): Frequently Asked Questions. Updated Jan 2023. Accessed Dec 12, 2023. https://www.acog.org/womens-health/faqs/urinary-tract-infections     
  6. Epp A, Larochelle A. No. 250-Recurrent Urinary Tract Infection. J Obstet Gynaecol Can. 2017 Oct;39(10):e422-e431. doi: 10.1016/j.jogc.2017.08.017. PMID: 28935065. 
  7. Gupta K. Recurrent simple cystitis in women. UpToDate. Wolters Kluwer. Updated Aug 25, 2023. Accessed Dec 12, 2023. https://www.uptodate.com/contents/recurrent-simple-cystitis-in-women 

From the medSask Database 

  1. Amgen Medical Information telephone correspondence: 1-866-50AMGEN (502-6436) on July 22/22 
  2. Prolia. Product Monograph. Amgen Canada Inc.; 2010. Accessed Dec 14, 2023. https://pdf.hres.ca/dpd_pm/00068834.PDF   
  3. Osteoporosis Canada. Covid-19 Vaccination and Osteoporosis Drug Therapy. April 1, 2021. Accessed Dec 14, 2023. https://osteoporosis.ca/oc-blog/covid-19-vaccination-and-osteoporosis-drug-therapy/ 
  4. Royal Osteoporosis Society. Taking osteoporosis drug treatments alongside COVID and flu vaccines. Oct 10, 2023. Accessed Dec 14, 2023. https://theros.org.uk/latest-news/taking-osteoporosis-drug-treatments-alongside-covid-and-flu-vaccines/ 
  5. medSask. Immunosuppressive Potential of Medications NOT Including Oncological Agents. Updated Aug 31, 2022. Accessed Dec 14, 2023. https://medsask.usask.ca/sites/medsask/files/2023-02/immunosuppressive-medications%20%281%29.pdf 
  6. ASBMR: The American Society for Bone and Mineral Research.  Joint Guidance on COVID-19 Vaccination and Osteoporosis Management from the ASBMR, AACE, Endocrine Society, ECTS, IOF, and NOF. Accessed Dec 14, 2023. https://www.asbmr.org/about/statement-detail/joint-guidance-on-covid-19-vaccine-osteoporosis#:~:text=Denosumab%20(Prolia%C2%AE),site%20reactions%20with%20either%20treatment 
  7. Denosumab. In: Lexicomp. Wolters Kluwer. Updated Nov 15, 2023. Accessed Dec 14, 2023. https://online-lexi-com.cyber.usask.ca/lco/action/doc/retrieve/docid/patch_f/2773277?cesid=3Hvmwm8XngQ&searchUrl=%2Flco%2Faction%2Fsearch%3Fq%3Ddenosumab%26t%3Dname%26acs%3Dfalse%26acq%3Ddenosumab 

November 28, 2023: Vaccine Errors, Ozempic Shortage, Methadone

Read Now

https://mailchi.mp/usask.ca/medsask-newsletter-november-28-2023?e=[UNIQID] 

Summary/Highlights
  • Respiratory Virus Season
    • Vaccine errors
    • Influenza antiviral prescribing
  • Drug Shortages
    • Carbamazepine suspension
    • Taro-dipyridamole/ASA capsule
    • Tirzepatide (Mounjaro®) injection
    • Semaglutide (Ozempic®) injection 
  • Professional Practice
    • Methadone generics
    • Managing drug interactions
  • From the medSask Database 
    • What medications and vaccines can pharmacists inject in Saskatchewan?
    • Ally's resource share: Canadian Paediatric Society website
  • Share your feedback with medSask! Help us create a valuable newsletter each month by completing a short (2-minute) survey.
References
  1. eHealth Saskatchewan. Saskatchewan Immunization Manual. Government of Saskatchewan. 2023. Accessed November 21, 2023. https://www.ehealthsask.ca/services/Manuals/Pages/SIM.aspx
  2. BC Centre for Disease Control. Guidance document on the management of inadvertent vaccine errors. Provincial Health Services Authority. Updated February 4, 2022. Accessed November 21, 2023. https://medicalstaff.islandhealth.ca/sites/default/files/covid-19/vaccine/Guidance-management-inadvertent-vaccine-errors-feb-4-2022.pdf
  3. SCPP. Community pharmacy practice enactments. Saskatchewan College of Pharmacy Professionals. Updated November 10, 2023. Accessed November 21, 2023. https://saskpharm.ca/document/5894/Community_Pharmacy_Practice_Enactments.pdf
  4. Drug Plan and Extended Benefits. Pharmacy Information: Listing of Generic Commercially Available Methadone Products. Saskatchewan Ministry of Health; October 31, 2023. Bulletin No. 863.
  5. Crawley A, Haines A, Smart T. Drug Interactions. RxFiles. University of Saskatchewan. May 2023. Accessed Nov 23, 2023. https://www-rxfiles-ca.cyber.usask.ca/RxFiles/uploads/documents/members/Cht-Drug-Interactions.pdf 
  6. Pharmacist’s Letter Canada. Follow These Rules of Thumb to Manage Drug Interactions. Feb 2017. Accessed Nov 23, 2023. https://ca-pharmacist.therapeuticresearch.com/Content/Articles/PLC/2017/Feb/Follow-These-Rules-of-Thumb-to-Manage-Drug-Interactions   
  7. Pharmacist’s Letter Canada. Drug Interactions: A Practical Approach. Feb 2017. Accessed Nov 23, 2023. https://ca-pharmacist.therapeuticresearch.com/Content/Segments/PRL/2017/Feb/Drug-Interactions-A-Practical-Approach-10676   
  8. Crawley A, Jin M. Migraine. RxFiles. University of Saskatchewan. July 2023. Accessed Nov 23, 2023. https://www-rxfiles-ca.cyber.usask.ca/RxFiles/uploads/documents/members/CHT-MIGRAINE.pdf 
  9. Downey S, Jensen B, Regier L. QT Prolongation and Torsades de Pointes. RxFiles. University of Saskatchewan. July 2023. Accessed Nov 23, 2023. https://www-rxfiles-ca.cyber.usask.ca/RxFiles/uploads/documents/members/cht-QA%20TORSADESdePoint.pdf 
  10. Foong AL, Grindrod KA, Patel T, Kellar J. Demystifying serotonin syndrome (or serotonin toxicity). Can Fam Physician. 2018 Oct;64(10):720-727. PMID: 30315014; PMCID: PMC6184959.
  11. Saskatchewan College of Pharmacy Professionals. Administration of Drugs by Injection and Other Routes Guidelines. Updated June 27, 2023. Accessed Nov 28, 2023. https://saskpharm.ca/document/3614/REF_Injection_Admin_Gdlns_20171213.pdf 
  12. Saskatchewan College of Pharmacy Professionals. Administration of Drugs by Injection and Other Routes FAQs. Updated June 27, 2023. Accessed Nov 28, 2023. https://www.saskpharm.ca/document/3615/REF_Injections_Admin_FAQs.pdf 
  13. Depo-Testosterone. Product Monograph. Pfizer Canada Inc.; 2018. Accessed Nov 28, 2023. https://pdf.hres.ca/dpd_pm/00046306.PDF 
  14. Botox. Product Monograph. AbbVie Corporation; 2022. Accessed Nov 28, 2023. https://pdf.hres.ca/dpd_pm/00069785.PDF   

October 31, 2023: Respiratory Virus Season, Drug Shortages, Ghost Tablets

Read Now

https://mailchi.mp/usask.ca/medsask-newsletter-october-31-2023?e=[UNIQID] 

Summary/Highlights
  • Respiratory Virus Season
    • Giving vaccines concomitantly
    • Updated vaccine screening and consent form
    • Pfizer Comirnaty® Omicron XBB.1.5 for children ≥ 5 to < 12 years
    • Respiratory virus webinar
    • RSV vaccine prescribing
  • Saskatchewan Biosimilars Initiative
    • Humalog® to Admelog® transition
  • Drug Shortages
    • Estring® vaginal ring
    • Cholestyramine powder
    • Prazosin tablets
  • Minor Ailments
    • Exceeding the drug plan minor ailment fee threshold
  • Professional Practice
    • Ghost tablets
  • From the medSask Database
    • Dexamethasone for children: alternatives to elixir
    • Amanda's resource share: Geri-Rx Files Medication Administration Challenges in Oral Adults
  • Share your feedback with medSask! Help us create a valuable newsletter each month by completing a short (2-minute) survey.
References
  1. Public Health Agency of Canada. Contents of immunizing agents authorized for use in Canada. Canadian Immunization Guide. Updated February 2023. Accessed October 25, 2023. https://www.canada.ca/en/public-health/services/publications/healthy-living/canadian-immunization-guide-part-1-key-immunization-information/page-15-contents-immunizing-agents-available-use-canada.html
  2. Saskatchewan Health. Chapter 8 – administration of biological products. Saskatchewan Immunization Manual. Updated February 2020. Accessed October 25, 2023. https://www.ehealthsask.ca/services/Manuals/Documents/sim-chapter8.pdf 
  3. Ask the experts. Immunize.org. Updated September 10, 2023. Accessed October 25, 2023. https://www.immunize.org/askexperts/experts_inf.asp
  4. Comirnaty Omicron XBB.1.5. Product Monograph. BioNTech Manufacturing GmbH. Distributed by Pfizer Canada ULC; 2023. Accessed October 26, 2023. https://covid-vaccine.canada.ca/info/pdf/comirnaty-omicron-xbb-1-5-pm-en.pdf
  5. Ghost Tablets. Pharmacist’s Letter Canada. Therapeutic Research Center. March 2013. Accessed October 25, 2023. https://ca-pharmacist.therapeuticresearch.com/Content/Segments/PRL/2013/Mar/Ghost-Tablets-5373
  6. Tungaraza TE, Talapan-Manikoth P, Jenkins R. Curse of the ghost pills: the role of oral controlled-release formulations in the passage of empty intact shells in faeces. Two case reports and a literature review relevant to psychiatry. Ther Adv Drug Saf. 2013 Apr;4(2):63-71. doi: 10.1177/2042098612474681. 
  7. MedSafe. New Zealand Medicines and Medical Devices Safety Authority. Ghosts of Medicines Passed. Published June 2, 2016. Accessed Oct 25, 2023. https://www.medsafe.govt.nz/profs/PUArticles/June2016/GhostsOfMedicinesPassed.htm
  8. Pms-Dexamethasone Elixir. Product Monograph. Pharmascience Inc.;2022. Accessed Oct 23, 2023. https://pdf.hres.ca/dpd_pm/00066494.PDF      
  9. Canadian Pediatric Society. Managing an acute asthma exacerbation in children (Table 2: Medications and dosages for acute asthma treatments by health care providers in children older than 1 year). Updated May 3, 2022. Accessed Oct 23, 2023. https://cps.ca/uploads/documents/Table_2._Medications_and_dosages_for_acute_asthma_treatments_by_health_care_providers_in_children_older_than_1_year_.docx_.pdf   
  10. Stovel J. Can Kids Be Given Injectable Dexamethasone Orally? MedScape. Feb 23, 2012. Accessed Oct 23, 2023. https://www.medscape.com/viewarticle/758927?src=mp&spon=30#vp_2 
  11. Medication Administration Challenges in Older Adults: To Crush or Not to Crush List. Geri-RxFiles. 3rd ed. University of Saskatchewan; 2019.  Accessed Oct 23, 2023. https://www.rxfiles.ca/RxFiles/uploads/documents/members/Geri-RxFiles-CrushDocument.pdf 
  12. Alberta College of Pharmacy. Caution: dose volumes for pediatric patients. Feb 10, 2015. Accessed Oct 23, 2023. https://abpharmacy.ca/articles/caution-dose-volumes-pediatric-patients 
  13. ISMP Canada. ISMP Canada Safety Bulletin: Volume 23, Issue 10. Oct 11, 2023. Accessed Oct 23, 2023. https://ismpcanada.ca/wp-content/uploads/ISMPCSB2023-i10-Clonidine-Compounding-1.pdf?utm_source=safetybulletin&utm_medium=email&utm_campaign=sbv23i10#page=5 
  14. Giving Meds by Alternative Routes. Pharmacist’s Letter Canada. Therapeutic Research Center. Feb 2020. Accessed Oct 30, 2023. https://ca-pharmacist.therapeuticresearch.com/Content/Segments/PRL/2015/Feb/Giving-Meds-by-Alternative-Routes-8122   

September 26, 2023: Vaccine/Injection Tips, Oral phenylephrine, Cystitis MA Update

Read Now

https://mailchi.mp/usask.ca/medsask-newsletter-september-26-2023?e=[UNIQID]  

Summary/Highlights
  • Respiratory Virus Season
    • Vaccine and injection tools you should be using this fall
  • Drug Shortages 
    • Ozempic® 1mg pen: shortage documents for diabetes and obesity
    • Tamsulosin SR capsules
  • Minor Ailments 
    • Cystitis update 
  • Professional Practice 
    • Oral phenylephrine: It'SNot effective 
  • New Information from Past Newsletters 
    • Domperidone safety review completed by Health Canada
  • From the medSask Database 
    • Safety of combination treatment with tranexamic acid (TXA) and combined hormonal contraceptives (CHCs) for reducing menstrual blood loss 
    • Kaitlyn's Resource Share: Natural Medicines Database 
  • Share your feedback with medSask! Help us create a valuable newsletter each month by completing a short (2-minute) survey.
References
  1. Thirion D. Viral Rhinitis, Influenza, Rhinosinusitis and Pharyngitis. CPS. Canadian Pharmacists Association. Updated May 1, 2018. Accessed September 21, 2023. https://cps.pharmacists.ca/new/documents/MA_CHAPTER/en/v_rhinitis_flu_sinusitis_pharyngitis
  2. FDA Briefing Document. Efficacy of Oral Phenylephrine as a Nasal Decongestant. Accessed Sept 21, 2023. https://www.fda.gov/media/171915/download
  3. US Food & Drug Administration. FDA clarifies results of recent advisory committee meeting on oral phenylephrine. Sept 14, 2023. Accessed Sept 21, 2023. https://www.fda.gov/drugs/drug-safety-and-availability/fda-clarifies-results-recent-advisory-committee-meeting-oral-phenylephrine
  4. Hatton RC, Winterstein AG, McKelvey RP, Shuster J, Hendeles L. Efficacy and safety of oral phenylephrine: systematic review and meta-analysis. Ann Pharmacother. 2007 Mar;41(3):381-90. doi: 10.1345/aph.1H679
  5. Horak F, Zieglmayer P, Zieglmayer R, Lemell P, Yao R, Staudinger H, Danzig M. A placebo-controlled study of the nasal decongestant effect of phenylephrine and pseudoephedrine in the Vienna Challenge Chamber. Ann Allergy Asthma Immunol. 2009 Feb;102(2):116-20. doi: 10.1016/S1081-1206(10)60240-2.
  6. Eccles R, Jawad MS, Jawad SS, Angello JT, Druce HM. Efficacy and safety of single and multiple doses of pseudoephedrine in the treatment of nasal congestion associated with common cold. Am J Rhinol. 2005 Jan-Feb;19(1):25-31. doi:10.1177/194589240501900105
  7. Summar Safety Review – Domperidone Assessing the Potential Risk of Psychiatric Withdrawal Events when Used for Lactation Stimulation. Health Canada. Updated September 27, 2023. Accessed September 21, 2023. https://dhpp.hpfb-dgpsa.ca/review-documents/resource/SSR1691692252806
  8. ACOG committee opinion no. 557: Management of acute abnormal uterine bleeding in nonpregnant reproductive-aged women. Obstet Gynecol. 2013 Apr;121(4):891-896. doi: 10.1097/01.AOG.0000428646.67925.9a.
  9. Kaunitz A. Abnormal uterine bleeding in nonpregnant reproductive-age patients: management. UpToDate. Wolters Kluwer. Updated August 29, 2023. Accessed September 12, 2023. https://www.uptodate.com/contents/abnormal-uterine-bleeding-in-nonpregnant-reproductive-age-patients-management
  10. Tranexamic acid. In: Lexicomp. Wolters Kluwer. Updated September 19, 2023. Accessed September 19, 2023. https://online-lexi-com.cyber.usask.ca/lco/action/doc/retrieve/docid/patch_f/7798
  11. Cyklokapron. Product Monograph. Pfizer Canada ULC; 2021. Accessed September 12, 2023. https://pdf.hres.ca/dpd_pm/00063720.PDF
  12. Singh S, Best C, Dunn S, Leyland N, Wolfman WL. No. 292-Abnormal Uterine Bleeding in Pre-Menopausal Women. J Obstet Gynaecol Can. 2018 May;40(5):e391-e415. doi: 10.1016/j.jogc.2018.03.007.
  13. WOMAN Trial Collaborators. Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial. Lancet. 2017 May 27;389(10084):2105-2116. doi: 10.1016/S0140-6736(17)30638-4.
  14. Lindoff C, Rybo G, Astedt B. Treatment with tranexamic acid during pregnancy, and the risk of thrombo-embolic complications. Thromb Haemost. 1993 Aug 2;70(2):238-40. Accessed September 19, 2023. PMID: 8236125.
  15. Meaidi A, Mørch L, Torp-Pedersen C, Lidegaard O. Oral tranexamic acid and thrombosis risk in women. EClinicalMedicine. 2021 May 6;35:100882. doi: 10.1016/j.eclinm.2021.100882.
  16. Thorne JG, James PD, Reid RL. Heavy menstrual bleeding: is tranexamic acid a safe adjunct to combined hormonal contraception? Contraception. 2018 Jul;98(1):1-3. doi: 10.1016/j.contraception.2018.02.00

August 29, 2023: COVID-19 Vaccine Update, Drug Shortages, and Medication Overdoses

Read Now

https://mailchi.mp/usask.ca/medsask-newsletter-august-29-2023 

Summary/Highlights
  • COVID-19 Testing and Tracking
  • Drug Shortages
    • Medroxyprogesterone oral tablets: shortage document
    • Clindamycin 1%/benzoyl peroxide 5% gel
    • Ipratropium 0.03% nasal spray
    • Nitrofurantoin
    • Diastat® rectal gel
    • Now available: Propranolol LA capsules!
  • Professional Practice
    • First RSV vaccine approved in Canada
    • Interpreting laboratory tests for medication management
  • From the medSask Database 
    • Determining presence of gluten in medications
    • Dorothy's Resource Share: SwitchRx
  • Share your feedback with medSask! Help us create a valuable newsletter each month by completing a short (2-minute) survey.
References
  1. Government of Saskatchewan. COVID-19 Testing and Treating Information – Self-Testing. Accessed Aug 28, 2023. https://www.saskatchewan.ca/government/health-care-administration-and-provider-resources/treatment-procedures-and-guidelines/emerging-public-health-issues/2019-novel-coronavirus/testing-information/rapid-testing
  2. Ontario Science Table. Use of Rapid Antigen Tests during the Omicron Wave. Feb 10, 2023. Accessed Aug 28, 2023. https://covid19-sciencetable.ca/sciencebrief/use-of-rapid-antigen-tests-during-the-omicron-wave/
  3. Government of Canada. Authorized medical devices for uses related to COVID-19: List of authorized testing devices. Updated May 18, 2023. Accessed Aug 28, 2023. https://www.canada.ca/en/health-canada/services/drugs-health-products/covid19-industry/medical-devices/authorized/list.html
  4. US Food and Drug Administration. At-Home COVID-19 Antigen Tests-Take Steps to Reduce Your Risk of False Negative Results: FDA Safety Communication. Updated Nov 17, 2022. Accessed Aug 28, 2023. https://www.fda.gov/medical-devices/safety-communications/home-covid-19-antigen-tests-take-steps-reduce-your-risk-false-negative-results-fda-safety
  5. Health Canada. Updated policy position COVID-19 rapid antigen self-testing devices used for serial testing: Notice to industry. Updated Oct 14, 2022. Accessed Aug 29, 2023. https://www.canada.ca/en/health-canada/services/drugs-health-products/covid19-industry/medical-devices/testing/notice-updated-policy-rapid-antigen-self-testing-devices-serial.html
  6. GlaxoSmithKline Inc. GSK’s Arexvy, the first respiratory syncytial virus (RSV) vaccine for older adults approved in Canada. Aug 4, 2023. Accessed Aug 24, 2023. https://ca.gsk.com/en-ca/media/press-releases/gsk-s-arexvy-the-first-respiratory-syncytial-virus-rsv-vaccine-for-older-adults-approved-in-canada/
  7. Arexvy. Product Monograph. GlaxoSmithKline. 2023. Accessed Aug 24, 2023. https://pdf.hres.ca/dpd_pm/00071904.PDF
  8. Health Canada. Respiratory syncytial virus (RSV). Canadian Immunization Guide. Updated Aug 11, 2023. Accessed Aug 24, 2023. https://www.canada.ca/en/public-health/services/publications/healthy-living/canadian-immunization-guide-part-4-active-vaccines/respiratory-syncytial-virus.html
  9. Gluten in meds. Pharmacist's Letter Canada. Therapeutic Research Center. June 2019. Accessed August 9, 2023. https://ca-pharmacist.therapeuticresearch.com/Content/Segments/PRL/2019/Jun/Gluten-in-Meds-S1906001
  10. Health Canada. Health Canada's Position on Gluten-Free Claims. Government of Canada. Updated May 29, 2012. Accessed August 9, 2023. https://www.canada.ca/en/health-canada/services/food-nutrition/food-safety/food-allergies-intolerances/celiac-disease/health-canada-position-gluten-free-claims.html
  11. Celiac Disease Foundation. Gluten in Medicine, Vitamins & Supplements. Accessed August 9, 2023. https://celiac.org/gluten-free-living/gluten-in-medicine-vitamins-and-supplements/

July 25, 2023: COVID-19 Vaccine Update, Drug Shortages, and Medication Overdoses

Read Now

https://mailchi.mp/usask.ca/medsask-newsletter-july-25-2023 

Summary/Highlights
References
  1. COVID-19 Program Update – mRNA Bivalent COVID-19 Vaccines for Primary Immunization Series for All Ages as of July 24, 2023; Dr. Saqib Shahab, Chief Medical Health Officer; July 19, 2023  https://www.ehealthsask.ca/services/Manuals/Documents/COVID-19%20Update%20-%20Bivalent%20Vaccines%20for%20Primary%20Series%20all%20ages%202023-07-19.pdf
  2. Johne M. Yanked from the market: Janssen withdraws its COVID vaccine from Canada. Canadian Healthcare Network. July 7, 2023. Accessed July 8, 2023. https://www.canadianhealthcarenetwork.ca/yanked-market-janssen-withdraws-its-covid-vaccine-canada 
  3. Immunizer Updates. Saskatchewan Health Authority. Updated July 6, 2023. Accessed July 8, 2023. https://www.saskhealthauthority.ca/system/files/2021-06/CV-19-G0125-CV19-Immunizer-Updates.pdf
  4. Guidance on the use of COVID-19 vaccines in the fall of 2023. Summary of National Advisory Committee on Immunization (NACI). Public Health Agency of Canada. Published July 11, 2023.  Accessed July 11, 2023. https://www.canada.ca/content/dam/phac-aspc/documents/services/publications/vaccines-immunization/national-advisory-committee-immunization-july-11-2023-guidance-use-covid-19-vaccines-fall/summary.pdf
  5. Dawood MY. Primary dysmenorrhea: advances in pathogenesis and management. Obstet Gynecol. 2006 Aug;108(2):428-41. doi: 10.1097/01.AOG.0000230214.26638.0c.
  6. Pattanittum P, Kunyanone N, Brown J, Sangkomkamhang US, Barnes J, Seyfoddin V, Marjoribanks J. Dietary supplements for dysmenorrhoea. Cochrane Database Syst Rev. 2016 Mar 22;3(3):CD002124. doi: 10.1002/14651858.CD002124.pub2. 
  7. Brown T. Dysmenorrhea. CPS. Canadian Pharmacists Association. Revised Aug 1 2020. Accessed July 23, 2023. https://www-e-therapeutics-ca.cyber.usask.ca/new/documents/MA_CHAPTER/en/dysmenorrhea_minor
  8. DynaMed. Dysmenorrhea. EBSCO Information Services. Accessed July 23, 2023. https://www-dynamed-com.ezproxy.shirp.ca/condition/dysmenorrhea
  9. Burnett MA, Antao V, Black A, Feldman K, Grenville A, Lea R, Lefebvre G, Pinsonneault O, Robert M. Prevalence of primary dysmenorrhea in Canada. J Obstet Gynaecol Can. 2005 Aug;27(8):765-70. doi: 10.1016/s1701-2163(16)30728-9. 
  10. Chapter 10: Biological Products. Saskatchewan Immunization Manual. Government of Saskatchewan Ministry of Health. Updated June 2023. Accessed July 11, 2023. https://www.ehealthsask.ca/services/Manuals/Documents/sim-chapter10.pdf
  11. Public health level recommendations on the use of pneumococcal vaccines in adults, including the use of 15-valent and 20-valent conjugate vaccines. Summary of National Advisory Committee on Immunization (NACI). Public Agency of Canada. Published February 2023. Accessed July 11, 2023. https://www.canada.ca/content/dam/phac-aspc/documents/services/immunization/national-advisory-committee-on-immunization-naci/summary-february-24-2023.pdf
  12. Transdermal Patches. Pharmacist's Letter Canada. Therapeutic Research Center. June 2021. Accessed July 8, 2023. https://ca-pharmacist.therapeuticresearch.com/Content/Segments/PRL/2012/Aug/Transdermal-Patches-4648
  13. Drug product database online query. Health Canada. 2023. Accessed July 8, 2023. https://health-products.canada.ca/dpd-bdpp/
  14. Characteristics of Transdermal Patches. Pharmacist's Letter Canada. Therapeutic Research Center. August 2021. Accessed July 8, 2023. https://ca-pharmacist.therapeuticresearch.com/Content/Segments/PRL/2012/Aug/Characteristics-of-Transdermal-Patches-4687
  15. Dos and Don'ts With Patches. Pharmacist's Letter Canada. Therapeutic Research Center. August 2021. Accessed July 8, 2023. https://ca-pharmacist.therapeuticresearch.com/Content/Segments/PRL/2012/Aug/Characteristics-of-Transdermal-Patches-4687
  16. Weibe A, Regier L. Opioid Analgesics: Drug Comparison Chart. RxFiles. University of Saskatchewan. Updated July 2023. Accessed July 8, 2023. https://www.rxfiles.ca/RxFiles/uploads/documents/members/CHT-Opioid.pdf 

June 27, 2023: Drug Shortages, Topical Hydrocortisone Update, and Shingrix

Read Now

https://mailchi.mp/usask.ca/medsask-newsletter-june-27-2023?e=[UNIQID] 

Summary/Highlights
  • Saskatchewan Biosimilars Initiative
    • Key points about what is happening in SHA facilities
  • Drug Shortages
    • Verapamil SR tablets
    • Permethrin 5% cream/lotion
  • Minor Ailments
    • Preventing and treating tinea pedis
  • Professional Practice
    • The pharmacy professional’s role in heat-related illness
  • New Information From Past Newsletters
    • Topical hydrocortisone scheduling
  • From the medSask database 
    • Scheduling Shingrix® vaccination following a shingles infection
    • Kelly's resource share: RxFiles gems
  • Share your feedback with medSask! Help us create a valuable newsletter each month by completing a short (2-minute) survey.
References
  1. Vaccines and Related Biological Products Advisory Committee June 15, 2023 Meeting Announcement. FDA. Accessed June 20, 2023. https://www.fda.gov/advisory-committees/advisory-committee-calendar/vaccines-and-related-biological-products-advisory-committee-june-15-2023-meeting-announcement
  2. COVID-19 epidemiology update: Testing and variants. Health Canada. Government of Canada. Updated June 20, 2023. Accessed June 20, 2023. https://health-infobase.canada.ca/covid-19/testing-variants.html
  3. Jetelina K. FDA’s fall 2023 vaccine plan. Your Local Epidemiologist. June 15, 2023. Accessed 20 June 2023. https://yourlocalepidemiologist.substack.com/p/fdas-fall-2023-vaccine-plan
  4. Medication Administration Challenges in Older Adults: Dosage Form Alterations. Geri RxFiles 3rd Edition. University of Saskatchewan. Accessed June 21, 2023. https://www.rxfiles.ca/RxFiles/uploads/documents/members/Geri-RxFiles-CrushDocument.pdf
  5. DynaMed. Scabies. EBSCO Information Services. Accessed June 2, 2023. https://www.dynamed.com/condition/scabies
  6. Miller P. Parasitic Skin Infections: Lice and Scabies. CPS. Canadian Pharmacists Association. Updated March 6, 2023. Accessed June 2, 2023. https://www.e-therapeutics.ca/search#ManagementOfScabies-CA65961B:~:text=All%20Figures-,Parasitic%20Skin%20Infections%3A%20Lice%20and%20Scabies,-Penny%20F.%20Miller
  7. Goldstein B, Goldstein A. Scabies: Management. UpToDate. Wolters Kluwer. Updated October 31, 2022. Accessed June 2, 2023. https://www.uptodate.com/contents/scabies-management?search=scabies%20treatment&source=search_result&selectedTitle=1~100&usage_type=default&display_rank=1#H4097880160 . Subscription required. 
  8. Crawley A, Bourassa J, Jensen B. Head Lice & Scabies. RxFiles. University of Saskatchewan. Updated November 2022. Accessed June 2, 2023. https://www.rxfiles.ca/RxFiles/uploads/documents/members/cht-Lice.pdf
  9. Mallin A. Athlete's Foot. CPS. Canadian Pharmacists Association. Updated July 5, 2021. Accessed June 15, 2023. https://www.e-therapeutics.ca/search#d2e594:~:text=All%20Figures-,Athlete%E2%80%99s%20Foot,-Anne%20Mallin%2C%20RPh
  10. Tinea Pedis. DynaMed.  EBSCO Information Services. Accessed June 14, 2023. https://www.dynamed.com/condition/tinea-pedis#GUID-0079EF2F-7F9C-4168-BD24-E76E0294DBF9
  11. Tinea Pedis (Athlete's Foot) Guidelines for Prescribing Topical Antifungals. medSask. University of Saskatchewan. Updated February 17, 2021. Accessed June 15, 2023. https://medsask-usask-ca.cyber.usask.ca/professional-practice/restricted-guidelines/tinea-pedis-infection---guidelines-for-prescribing-topical-antifungals.php
  12. Health Canada. Extreme heat and human health: For pharmacists and pharmacy technicians. Government of Canada. 2021. Accessed June 20, 2023. https://www.canada.ca/en/health-canada/services/publications/healthy-living/extreme-heat-human-health-pharmacists-technicians.html
  13. NDS Policies. National Association of Pharmacy Regulatory Authorities (NAPRA). 2023. Accessed June 22, 2023. https://www.napra.ca/national-drug-schedules/national-drug-schedules-program/nds-policies/
  14. Health Canada. Notice – Prescription Drug List (PDL): Hydrocortisone. Government of Canada. December 24, 2014. Accessed June 22, 2023. https://www.canada.ca/en/health-canada/services/drugs-health-products/drug-products/prescription-drug-list/notice-hydrocortisone.html
  15. Herpes zoster (shingles). Canadian Immunization Guide. Government of Canada. Updated August 2018. Accessed May 1, 2023. https://www.canada.ca/en/public-health/services/publications/healthy-living/canadian-immunization-guide-part-4-active-vaccines/page-8-herpes-zoster-(shingles)-vaccine.html#a5
  16.  Jin M. Q&A Summary, Non-Live Recombinant Herpes Zoster Vaccine (Shingrix). RxFiles. University of Saskatchewan. Updated May 2021. Accessed May 1, 2023. https://www.rxfiles.ca/RxFiles/uploads/documents/Shingrix_QandA.pdf
  17. Shingles Vaccination. National Center for Immunization and Respiratory Diseases. Centers for Disease Control and Prevention.  Updated May 8, 2023. Accessed May 10, 2023. https://www.cdc.gov/vaccines/vpd/shingles/public/shingrix/index.html#:~:text=If%20you%20had%20shingles%20in,gone%20away%20before%20getting%20vaccinated.
  18. Timing of vaccine administration. Canada Immunization Guide. Government of Canada. Updated May 2017. Accessed May 10, 2023. https://www.canada.ca/en/public-health/services/publications/healthy-living/canadian-immunization-guide-part-1-key-immunization-information/page-10-timing-vaccine-administration.html#p1c9a2  
     

May 30th, 2023: Drug Shortages, Sun Screen, and Trans Health

Read Now

https://mailchi.mp/15246b5039fd/medsask-newsletter-may-30-6245409?e=[UNIQID] 

Summary/Highlights
  • Saskatchewan Biosimilars Initiative 
    • Troubleshooting tools
    • BTIF fee is still active 
  • Drug Shortages 
    • Prazosin tablets
    • Metadol-D® liquid 
  • Minor Ailments 
    • Managing mosquito bites
  • Professional Practice 
    • Sun safety and sunscreens
    • Highlighting Trans Health Resources 
  • New Information From Past Newsletters 
    • One-way flow of filter needles
  • From the medSask database 
    • Measuring methadone using oral syringes 
    • Janice's Resource Share: Thrombosis Canada 
  • Share your feedback with medSask! Help us create a valuable newsletter each month by completing a short (2-minute) survey.
References
  1. Transitioning to A Biosimilar: Assessment of Unexpected Response. medSask. University of Saskatchewan. Accessed May 27, 2023. https://medsask.usask.ca/sites/medsask/files/2023-05/medSask_TransitioningtoBiosimilar_AssessofUnexpectedResponse_May1%2C2023.pdf
  2. How To Make The Most Of Your Biosimilar. medSask. University of Saskatchewan. Accessed May 27, 2023. https://medsask.usask.ca/sites/medsask/files/2023-05/medSask_MakeMostofBiosimiliar_May%205%202023%20%28003%29.pdf
  3. Drug Shortages and Discontinuations. medSask. University of Saskatchewan. Updated March 27, 2023. Accessed May 27, 2023.  https://medsask.usask.ca/professional-practice/drug-shortages
  4. Commercially Available Methadone for Opioid Agonist Therapy (OAT): Pharmacist Information. medSask, CPDPP. University of Saskatchewan. Updated April 13, 2023. Accessed May 27, 2023. https://medsask.usask.ca/sites/medsask/files/2023-04/commercial-methadone-pharmacist-info.pdf
  5. DynaMed. Insect Bites and Stings. EBSCO Information Services. Accessed May 26, 2023. https://www.dynamed.com/condition/insect-bites-and-stings
  6. DynaMed. Mosquito Avoidance. EBSCO Information Services. Accessed May 26, 2023. https://www.dynamed.com/prevention/mosquito-avoidance
  7. Kleiman, N. Insect Bites and Stings. In: Minor Ailments [Internet]. Ottawa (ON): Canadian Pharmacists Association; c2021 [updated 13 Jan 2023; cited 26 May 2023]. Available from http://www.myrxtx.ca. Also available in paper copy from the publisher.
  8. Be Ready for Questions about Insect and Tick Repellents. Pharmacist’s Letter Canada June 2022. Accessed 26 May 2023. 
  9. Effectiveness checker. Ulbricht K, Basch E, editors. Online Natural Medicines[Internet]. Somerville (MA); c2020 [cited 26 May 2023]. Available from: https://naturalmedicines.therapeuticresearch.com/  Subscription required.
  10. Ives AR, Paskewitz SM; Inter-L&S 101; Biology Interest Groups; Entomology Class 201. Testing vitamin B as a home remedy against mosquitoes. J Am Mosq Control Assoc. 2005 Jun;21(2):213-7. doi: 10.2987/8756-971X(2005)21[213:TVBAAH]2.0.CO;2. PMID: 16033124.
  11. Kleiman, N. Prevention and Treatment of Sun-Induced Skin Damage. eCPS. Canadian Pharmacists Association. Updated August 18, 2022. Accessed May 1, 2023. https://www-e-therapeutics-ca.cyber.usask.ca/search#:~:text=All%20Figures-,Prevention%20and%20Treatment%20of%20Sun%2DInduced%20Skin%20Damage,-Nancy%20Kleiman%2C%20BSP 
  12. Sun Safety for Every Day. Dermatology.ca. Canadian Dermatology Association. 2023. Accessed May 1, 2023. https://dermatology.ca/public-patients/sun-protection/sun-safety-every-day/
  13. Sunscreen 101. Dermatology.ca. Canadian Dermatology Association. https://dermatology.ca/wp-content/uploads/2018/06/Sunscreen-101-April-2018-8-5-x-14-EN.pdf
  14. Clinical Resource, Drug-Induced Photosensitivity. Pharmacist’s Letter/Pharmacy Technician’s Letter/Prescriber’s Letter. May 2023. [390509]. Subscription required.
  15. DynaMed. Sunburn. EBSCO Information Services. Accessed May 25, 2023. https://www.dynamed.com/condition/sunburn
  16. Rainbow Health Ontario. My guide to caring for trans and gender-diverse patients. Trans Primary Care. 2020. Accessed May 27, 2023. https://www.rainbowhealthontario.ca/TransHealthGuide/index.html#guidelines
  17. Coleman, E., Radix, A. E., Bouman, W.P., Brown, G.R., de Vries, A. L. C., Deutsch, M. B., Ettner, R., Fraser, L., Goodman, M., Green, J., Hancock, A. B., Johnson, T. W., Karasic, D. H., Knudson, G. A., Leibowitz, S. F., Meyer-Bahlburg, H. F.L., Monstrey, S. J., Motmans, J., Nahata, L., ... Arcelus, J. (2022). Standards of Care for the Health of Transgender and Gender Diverse People, Version 8. International Journal of Transgender Health, 23(S1), S1-S260. https://doi.org/10.1080/26895269.2022.2100644 
  18. Trans Care BC. Patient Materials. Provincial Health Services Authority. Accessed May 27, 2023. http://www.phsa.ca/transcarebc/health-professionals/pt-materials
  19. Ehrhardt, Kaitlin. Pharmacy Quick Guide to Gender Affirming Care in SK. University of Saskatchewan. Updated April 2023. Accessed May 27, 2023. https://drive.google.com/file/d/1mmPkLYoP41EkvJCsw1MwEC2tonDcWr9d/view
  20. Decision Support Tool: Drawing Medications from a Glass Ampoule and the Use of Filter Needles. Population and Public Health. Winnipeg Regional Health Authority. Published August 16, 2018. Accessed April 17, 2023. https://professionals.wrha.mb.ca/old/professionals/immunization/files/SupportMedicationsglassampoulefilterneedles.pdf
  21. Information Sheet: Filter Needles. PCH Medication Safety Working Group. Winnipeg Regional Health Authority. April 2015. Accessed May 1, 2023. https://professionals.wrha.mb.ca/old/professionals/immunization/files/FilterNeedles.pdf
  22. Opioid Agonist Therapy (OAT) Standards. Saskatchewan College of Pharmacy Professionals. Updated October 2020. Accessed May 1, 2023. https://www.saskpharm.ca/document/5871/REF_OAT_Standards.pdf
  23. Jordan MA, Choksi D, Lombard K, Patton LR. Development of Guidelines for Accurate Measurement of Small Volume Parenteral Products Using Syringes. Hospital Pharmacy. 2021;56(3):165-171. doi:10.1177/0018578719873869
  24. Thrombosis Canada. 2022. Accessed May 27, 2023. https://thrombosiscanada.ca/  
     

April 25th, 2023: Biosimilars, Mifegymiso, and Acute Migraine

Read Now

https://mailchi.mp/usask.ca/medsask-newsletter-april-25-2023?e=[UNIQID] 

Summary/Highlights
  • Drug Shortages 
    • Glucagon injectable
  • Saskatchewan Biosimilars Initiative
    • Insulin lispro comparison chart, biosimilar insulin safety labels, and adalimumab comparison chart
  • Professional Practice 
    • Minor ailments: managing acute migraine headache
    • Access to Mifegymiso
  • From the medSask database 
    • Alternative intramuscular injection sites
    • Filter needles and drawing up from ampules
    • Maya's resource share: A quick reference guide for pediatric and neonatal dosing information 
  • Share your feedback with medSask! Help us create a valuable newsletter each month by completing a short (2-minute) survey.
References

References are recorded in the order in which they appear. 

  1. Drug Shortages and Discontinuations. medSask. University of Saskatchewan. Updated April 17, 2023. Accessed April 17, 2023. https://medsask.usask.ca/professional-practice/drug-shortages
  2. Hypoglycemia: low blood sugar in adults. Diabetes Canada. Updated March 2018. Accessed April 17, 2023. https://guidelines.diabetes.ca/docs/patient-resources/hypoglycemia-low-blood-sugar-in-adults.pdf
  3. Regier L. Topical Corticosteroids: Comparison Chart. RxFiles. University of Saskatchewan. Updated December 2022. Accessed April 17, 2023. https://www.rxfiles.ca/RxFiles/uploads/documents/members/CHT-SteroidClassPotencyCOLOR.pdf
  4. Biosimilars in Saskatchewan. University of Saskatchewan. Updated April 2023. Accessed April 17, 2023. https://medsask.usask.ca/professional-practice/biosimilars-in-Saskatchewan
  5. Minor Ailment FAQs. medSask. University of Saskatchewan. Updated March 6, 2023. Accessed April 17, 2023. https://medsask.usask.ca/minor-ailment-guidelines/FAQshttps://medsask.usask.ca/minor-ailment-guidelines/FAQs
  6. Clinical Resource, Comparison of Triptans. Pharmacist’s Letter/Pharmacy Technician’s Letter. February 2021. [370229]
  7.  Clinical Resource, Oral Meds to Keep in Original Containers. Pharmacist’s Letter/Pharmacy Technician’s Letter/Prescriber’s Letter. April 2023. [390430]
  8. Foong AL, Grindrod KA, Patel T, Kellar J. Demystifying serotonin syndrome (or serotonin toxicity). Can Fam Physician. 2018 Oct;64(10):720-727. PMID: 30315014; PMCID: PMC6184959.
  9. Regier L, Jensen B, Downey S, Crawley A. MIGRAINE: Acute Therapy. RxFiles Drug Comparison Charts. Saskatoon, SK: University of Saskatchewan. [updated Nov 2022; accessed 20 Apr 2023].
  10. Worthington I, Pringsheim T, Gawel MJ, Gladstone J, Cooper P, Dilli E, Aube M, Leroux E, Becker WJ. Canadian Headache Society Guideline: acute drug therapy for migraine headache. Canadian Journal of Neurological Sciences. 2013 Sep;40(S3):S1-3.
  11. Schwedt T, Garza I. Acute treatment of migraine in adults. Post TW, ed. UpToDate. Waltham, MA: UpToDate Inc. https://www.uptodate.com   (Updated Mar 14 2023, Accessed 20 Apr 2023) Subscription required.
  12. Chen YS, Lee HF, Tsai CH, Hsu YY, Fang CJ, Chen CJ, Hung YH, Hu FW. Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis. Nutr Neurosci. 2022 Sep;25(9):1801-1812. doi: 10.1080/1028415X.2021.1904542. Epub 2021 Mar 29. PMID: 33779525.
  13.  DISPENSING MIFEGYMISO® Guidance for Pharmacy Professionals. SCPP Reference Manual. Updated April 2019, cited April 2023. Available from: https://scp.in1touch.org/document/3692/Mifegymiso_Dispensing_Gdlns_20170829.pdf
  14. Mifegymiso-Information for the prescribing physician. College of Physicians and Surgeons of Saskatchewan. Updated April 2019, cited April 2023. Available from: https://www.cps.sk.ca/iMIS/Documents/Mifegymiso%20-%20info%20for%20physicians%202019.pdf
  15. Mifegymiso Product Monograph. https://pdf.hres.ca/dpd_pm/00068788.PDF
  16. Administration of Drugs by Injection and Other Routes Guidelines. Saskatchewan College of Pharmacy Professionals. Updated September 26, 2022. Accessed April 13, 2023. https://www.saskpharm.ca/document/3614/REF_Injection_Admin_Gdlns_20171213.pdf 
  17. “Administration Routes, Sites, and Techniques”. In: Chapter 8 – Administration of Biological Products. Saskatchewan Immunization Manual. Government of Saskatchewan Ministry of Health. Updated February, 2022. Accessed March 20, 2023. https://www.ehealthsask.ca/services/manuals/Documents/sim-chapter8.pdf#page=17 
  18. Cornwall J. Are nursing students safe when choosing gluteal intramuscular injection locations? Australas Med J. 2011;4(6):315-21. doi: 10.4066/AMJ.2011764. Epub 2011 Jun 30. PMID: 23386894; PMCID: PMC3562949. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/.
  19. Medication Administration: Intramuscular Injection – CE. Elsevier Health. RELX Group. Published November 22, 2022. Accessed April 21, 2023. Available from: https://elsevier.health/en-US/preview/intramuscular-injections-acute-care#ref6 
  20. IM Ventrogluteal Adult FINAL. ImmunizeBC. September 25, 2014. Accessed March 20, 2023. https://youtube.com/watch?v=orBAy6Aqc9k&si=EnSIkaIECMiOmarE 
  21. Oberholzer W. Physicians and sensitive examinations. College of Physicians and Surgeons Saskatchewan. February 8, 2021. Accessed March 20, 2023. Available from: https://www.cps.sk.ca/iMIS/Documents/DocTalk/08.01/2021.02.08%20Sensitive%20examinations%20CPSS%20Guidance%20document.pdf 
  22.  “Appendix B – Administration of Biological Products”. Chapter 2: Immunization. Communicable Disease Control Manual. BC Centre for Disease Control. Updated June, 2022. Accessed March 20, 2023. http://www.bccdc.ca/resource-gallery/Documents/Guidelines%20and%20Forms/Guidelines%20and%20Manuals/Epid/CD%20Manual/Chapter%202%20-%20Imms/Appendix_B_Administration.pdf 
  23. Delatestryl [Prescribing Information]. Laval, Quebec. Valent International. 2014. Accessed March 20, 2023. https://pdf.hres.ca/dpd_pm/00026379.PDF 
  24. Abilify Maintena [Product Monograph]. Saint-Laurent, Quebec. Lundbeck Canada Inc. 2021. Accessed March 20, 2023. https://pdf.hres.ca/dpd_pm/00060200.PDF 
  25. Clopixol [Product Monograph]. Saint-Laurent, Quebec. Lundbeck Canada Inc. 2020. Accessed March 20, 2023. https://www.lundbeck.com/content/dam/lundbeck-com/americas/canada/products/files/clopixol_product_monograph_english.pdf 
  26. Risperidal Consta [Product Monograph]. Toronto, Ontario. Janssen Inc. 2017. Accessed April 13, 2023. https://pdf.hres.ca/dpd_pm/00040784.PDF 
  27. Haloperidol Deconate Injection [Product Monograph]. Etobicoke, Ontario. 2014. Accessed April 13, 2023. https://pdf.hres.ca/dpd_pm/00025917.PDF 
  28. Filtered Needles for Withdrawing Medication from Glass Ampoules: A Review fo the Cost Effectiveness and Incidence of Complications. Health Technology Inquiry Service. Canadian Agency for Drugs and Technologies in Health (CADTH). Published February 24, 2010. Accessed April 17, 2023. https://www.cadth.ca/sites/default/files/pdf/L0158_Filtered_needles_final_no_abs.pdf
  29. Standard for the Administration of Immunizations. Vaccine Administration Standards. Alberta Health Services. Updated January 1, 2020. Accessed April 17, 2023. https://www.albertahealthservices.ca/assets/info/hp/cdc/if-hp-cdc-ipsm-standard-administration-immunization-06-100.pdf
  30. Communicable Disease Control Manual. BC Centre for Disease Control. Updated June 2022. Accessed April 17, 2023. http://www.bccdc.ca/resource-gallery/Documents/Guidelines%20and%20Forms/Guidelines%20and%20Manuals/Epid/CD%20Manual/Chapter%202%20-%20Imms/Appendix_B_Administration.pdf
  31. Chapter 8: Administration of Biological Products. Saskatchewan Immunization Manual. Government of Saskatchewan Ministry of Health. Updated June 2018. Accessed April 17, 2023. https://www.ehealthsask.ca/services/manuals/Documents/sim-chapter8.pdf
  32. Decision Support Tool: Drawing Medications from a Glass Ampoule and the Use of Filter Needles. Population and Public Health. Winnipeg Regional Health Authority. Published August 16, 2018. Accessed April 17, 2023. https://professionals.wrha.mb.ca/old/professionals/immunization/files/SupportMedicationsglassampoulefilterneedles.pdf
  33. BC Children’s and Women’s Hospital (C&W) Online Formulary (PedMed). Department of Pharmacy. Children’s & Women’s Health Centre of British Columbia. Updated 2022. Accessed April 14, 2023. http://www.pedmed.org/DrugApp/index.html  

March 29, 2023: Flu Season, Ramadan, and COVID-19 Vaccine Update

Read Now

https://mailchi.mp/usask.ca/medsask-newsletter-march-29-2023?e=[UNIQID] 

Summary/Highlights
  • You can read the medSask newsletter in another language!
  • COVID-19 Vaccine Update
    • Moderna SpikevaxTM BA.4/5 off-label administration for children 6-17 years of age
    • Expanded booster dose eligibility for select populations
  • Drug Shortages
    • Nitroglycerin sublingual spray  
    • Teva-prazosin tablets
  • Saskatchewan Biosimilars Initiative
    • Minimizing medication errors
  • Professional Practice
    • Coronavirus, influenza, RSV…and now Seasonal Allergies!
    • Ramadan and Medication Use
    • Prevnar 20TM and Vaxneuvance® - What do pharmacists need to know?
  • From the medSask database
    • Beyond use date considerations for medications in vials
    • Sara's resource share – talking points for individuals interested in cannabis
  • Share your feedback with medSask! Help us create a valuable newsletter each month by completing a short (2-minute) survey.
References

References are recorded in the order in which they appear. 

  1. Permitted Off-label Administration of Moderna Spikevax BA.4/5 Bivalent Vaccine to Children 6-17 Years Old. Saskatchewan Ministry of Health. March 14, 2023. https://www.ehealthsask.ca/services/Manuals/Documents/Moderna%20Spikevax%20BA.45%20Bivalent%20off-label%20use%20permitted%20for%206-17%20years%202023-03-14.pdf
  2. Spring 2023 Second COVID-19 Bivalent Booster Dose Eligibility and Interval Recommendations. Saskatchewan Ministry of Health. Updated March 23, 2023. Accessed March 27, 2023. https://saskpharm.ca/document/10925/MoH_Second_Bivalent_COVID_Booster_Eligibility_20230323.pdf
  3. Drug Shortages and Discontinuations. medSask. University of Saskatchewan. Updated March 27, 2023. Accessed March 27, 2023. https://medsask.usask.ca/professional-practice/drug-shortages
  4. Patient Presents with Prescription for NTG Spray or Requests NTG Spray (schedule 2 drug). Canadian Cardiovascular Society and Canadian Cardiovascular Pharmacists Network. Updated March 17, 2023. Accessed March 27, 2023. https://ccs.ca/app/uploads/2023/03/Guidance-Tool_Shortage-of-Nitroglycerin-Sprays-in-Canada.pdf
  5. Shortage of Nitroglycerin Sprays In Canada. Recalls and Safety Alerts. Government of Canada. Updated March 17, 2023. Accessed March 22, 2023. https://recalls-rappels.canada.ca/en/alert-recall/shortage-nitroglycerin-sprays-canada
  6. Biosimilars in Saskatchewan. University of Saskatchewan. Updated March 2023. Accessed March 24, 2023. https://medsask.usask.ca/professional-practice/biosimilars-in-Saskatchewan
  7. DynaMed. Allergic Rhinitis. EBSCO Information Services. Accessed March 17, 2023. https://www.dynamed.com/condition/allergic-rhinitis. 
  8. Keith, P. Allergic Rhinitis. In: Therapeutics [Internet]. Ottawa (ON): Canadian Pharmacists Association; c2023 [updated Mar 2022; cited 2023 Mar 17]. Available from: http://www.myrxtx.ca. Also available in paper copy from the publisher.
  9.  Kendrick J. Allergic Rhinitis. In: Minor Ailments [Internet]. Ottawa (ON): Canadian Pharmacists Association; c2023 [updated Mar 2022; cited 2023 Mar 17]. Available from: http://www.myrxtx.ca . Also available in paper copy from the publisher.
  10. Abolaban H, Al-Moujahed A. Muslim patients in Ramadan: A review for primary care physicians. Avicenna J Med. 2017 Jul-Sep;7(3):81-87. doi: 10.4103/ajm.AJM_76_17. PMID: 28791239; PMCID: PMC5525471. 
  11. Grindrod K, Alsabbagh W. Managing medications during Ramadan fasting. Canadian Pharmacists Journal/Revue des Pharmaciens du Canada. 2017 May;150(3):146-9.
  12. Ramadan and Diabetes. Diabetes Canada Clinical Practice Guidelines. Published April 27, 2018. Accessed March 24, 2023. https://guidelines.diabetes.ca/healthcareprovidertools/ramadan-and-diabetes
  13. Akhtar AM, Ghouri N, Chahal CAA, Patel R, Ricci F, Sattar N, Waqar S, Khanji MY. Ramadan fasting: recommendations for patients with cardiovascular disease. Heart. 2022 Feb;108(4):258-265. doi: 10.1136/heartjnl-2021-319273. Epub 2021 May 14. PMID: 33990414; PMCID: PMC8819657.
  14. Pharmacy 5in5. Ramadan and Medication. University of Waterloo Faculty of Science School of Pharmacy. 2017. Accessed March 24, 2023. https://www.youtube.com/watch?v=LJ5qCgPJJ0U
  15. Summary of National Advisory Committee on Immunization (NACI) Statement of February 2023: Public health level recommendations on the use of pneumococcal vaccines in adults, including the use of 15-valent and 20-valent conjugate vaccines. Public Health Agency of Canada. Published February 24, 2023. Accessed March 14, 2023. https://www.canada.ca/content/dam/phac-aspc/documents/services/immunization/national-advisory-committee-on-immunization-naci/summary-february-24-2023.pdf
  16. An Advisory Committee Statement (ACS): Public health level recommendations on the use of pneumococcal vaccines in adults, including the use of 15-valent and 20-valent conjugate vaccines. Public Health Agency of Canada. Published February 24, 2023. Accessed March 14, 2023. https://www.canada.ca/content/dam/phac-aspc/documents/services/immunization/national-advisory-committee-on-immunization-naci/public-health-level-recommendations-use-pneumococcal-vaccines-adults-including-use-15-valent-20-valent-conjugate-vaccines/recomme
  17. Pneumococcal vaccine. Canadian Immunization Guide. Government of Canada. Updated February 28, 2023. Accessed March 14, 2023. https://www.canada.ca/en/public-health/services/publications/healthy-living/canadian-immunization-guide-part-4-active-vaccines/page-16-pneumococcal-vaccine.html
  18. Pneumococcal Vaccination Recommendations. medSask. University of Saskatchewan. Updated April 2015. Accessed March 14, 2023. Internal PDF.
  19. Prevnar 20 Health Care Professional Leaflet. Pfizer Canada ULC. 2023. Accessed March 16, 2023. https://webfiles.pfizer.com/ENPNR20HCPLEAFLET?referrer=3d560995-33e1-433f-85cf-a1638b95c2e7
  20. Disease Prevention and Travel Health Services Policy and Framework for Saskatchewan Pharmacists. Saskatchewan College of Pharmacy Professionals. Updated April 29, 2021. Accessed March 24, 2023. https://saskpharm.ca/document/5410/REF_Travel_Health_Disease_Prevention_Travel_Health_Services_Frmwk.pdf 
  21. Vaccine Preventable Disease and Travel Health. medSask. University of Saskatchewan. Accessed March 24, 2023.  https://medsask.usask.ca/restricted-guidelines/vaccine-preventable-disease-and-travel-health 
  22. Disease Prevention and Travel Health Services. Continuing Professional Development for Pharmacy Professionals. University of Saskatchewan. Accessed March 24, 2023. https://pharmacy-nutrition.usask.ca/cpdpp/continuing-education-/travel-health.php
  23. Model Standards for Pharmacy Compounding of Hazardous Sterile Preparations. National Association of Pharmacy Regulatory Authorities (NAPRA). Updated September 2016. Accessed March 14, 2023. https://www.napra.ca/wp-content/uploads/2022/09/NAPRA-Mdl-Stnds-Pharmacy-Compounding-Hazardous-Sterile-Preparations-Nov-2016-Revised-b.pdf
  24. Drug Product Database Online Query. Health Canada. Accessed March 23, 2023.  https://health-products.canada.ca/dpd-bdpp/
  25. Email communication with Bausch Health. Received March 22, 2023. 
  26. Cannabis for Medical Purposes: How to help patients find a safe and effective dose. Canadian Pharmacists Association. 2018. Accessed March 16, 2023. https://www.pharmacists.ca/cpha-ca/assets/File/education-practice-resources/Cannabis%20Dosing%20and%20Titrating%20Final_web.pdf
  27. Cannabis for Medical Purposes: How to Start the Conversation. Canadian Pharmacists Association. 2018. Accessed March 16, 2023. https://www.pharmacists.ca/cpha-ca/assets/File/cpha-on-the-issues/CannabisTool_StartConversation.pdf  

February 28, 2023: Biosimilars and Domperidone

Read Now

https://mailchi.mp/usask.ca/medsask-newsletter-february-28-2023?e=[UNIQID]

Summary/Highlights
  • Saskatchewan Biosimilars Initiative
    • Support tools for pharmacists: A-PAR, Insulin Glargine and Insulin Aspart Comparison Charts, and the Transitioning to a Biosimilar Insulin infographic
    • Register to receive the recording from the biosimilar insulin webinar
    • Live biosimilar Q&A: March 8th, 2023
  • Professional Practice
    • Domperidone Use in Breastfeeding/Chestfeeding: health care professional handout and patient handout
    • Need to Know Information about Norovirus
  • From the medSask database
    • A question from the lines: Alternatives to valproic acid capsules during drug shortage?
    • Shavan's resource share: Merck Manual Professional Version
References

References are recorded in the order in which they appear. 

  1. Biosimilars in Saskatchewan. University of Saskatchewan. Updated February 2023. Accessed February 14, 2023. https://medsask.usask.ca/professional-practice/biosimilars.php
  2. Sawin, S. Domperidone Use in Breastfeeding/Chestfeeding, Healthcare Professional Handout. medSask, University of Saskatchewan. Published January 20, 2023. Accessed February 14, 2023.  https://medsask.usask.ca/documents/domperidone-healthcare-professional-handout.pdf
  3. Sawin, S. Domperidone Use in Breastfeeding/Chestfeeding, Patient Handout. medSask, University of Saskatchewan. Published February 8, 2023. Accessed February 21, 2023.  https://medsask.usask.ca/documents/domperidone-healthcare-professional-handout.pdf
  4. National Collaborating Centre for Infectious Diseases. Disease Debrief – Norovirus. Updated January 23, 2023. Cited February 20, 2023. Available from https://nccid.ca/debrief/norovirus/
  5. Centers for Disease Control and Prevention. About Norovirus. Updated March 5, 2021. Cited February 20, 2023. Available from:   https://www.cdc.gov/norovirus/about/index.html
  6. Government of Canada. Pathogen safety data sheets: Infectious substances – Norovirus. Updated 11-24-2020. Accessed 02-20-2023. Available from:
  7. https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/norovirus-pathogen-safety-data-sheet.html#sec4
  8. Hughes C and Petrucha R.  Nausea and Vomiting. In: Therapeutic Choices [Internet]. Ottawa (ON): Canadian Pharmacists Association; c2023 [updated Apr 2021; cited 2023 Feb 20]. Available from: http://www.myrxtx.ca. Also available in paper copy from the publisher.
  9. Jobson MD. Alexandraki I, Smetana G. Acute viral gastroenteritis in adults. UpToDate. Wolters Kluwer. Accessed February 20, 2023. https://www.uptodate.com (Subscription required).
  10. O’Ryan M. Acute viral gastroenteritis in children in resource-rich countries: Management and prevention. UpToDate. Wolters Kluwer. Accessed February 20, 2023. https://www.uptodate.com (Subscription required).
  11. Nausea and Vomiting in Adults. EBSCO Information Services. Accessed February 20, 2023. https://www.dynamed.com/approach-to/nausea-and-vomiting-in-adults
  12. Acute Viral Gastroenteritis in Children. EBSCO Information Services. Accessed February 20, 2023. https://www.dynamed.com/condition/acute-viral-gastroenteritis-in-children
  13. Jensen B, Crawley A, LeBras M. Seizures: Antiseizure Drug Comparison Chart. RxFiles, University of Saskatchewan. Updated Jan 2023. Accessed February 17, 2023.
  14. Drug Shortages and Discontinuations. University of Saskatchewan. Updated February 14, 2023. Accessed February 17, 2023. https://medsask.usask.ca/professional-practice/drug-shortages.php
  15. Saskatchewan Drug Plan. Saskatchewan Online Formulary Database. Government of Saskatchewan, Regina, SK. Accessed February 17, 2023. http://formulary.drugplan.health.gov.sk.ca/SearchFormulary
  16. McKesson Canada. PharmaClik. Accessed February 17, 2023.  http://clients.mckesson.ca (Account required).
  17. Merck Manual Professional Version. Merck & Co., Inc.; 2023. Accessed February 14, 2023. https://www.merckmanuals.com/en-ca/professional

January 31, 2023: Drug Shortages and COVID-19 Booster Dose Eligibility

Read Now

https://mailchi.mp/usask.ca/medsask-newsletter-january-31-2023?e=[UNIQID]

Summary/Highlights
  • COVID-19 booster dose eligibility update
  • Drug shortages: testosterone and liquid antibiotic suspensions
  • Saskatchewan Biosimilars Initiative: biosimilar key points infographic 
  • From the medSask database
    • Dukoral® requires a prescription to dispense in Saskatchewan
    • Dispensing and prescribing Paxlovid® for out-of-province or out-of-country individuals
    • Completing a hepatitis A vaccine series
    • Kelsey’s Resource Share: Canadian Probiotic Chart
References

References are recorded in the order in which they appear. 

  1. Saskatchewan Ministry of Health. COVID-19 Booster Dose Clarification and Revision to Interval [Internet]. Regina, SK; [published 2023 Jan 26; cited 2023 Jan 31]. Available from: https://saskpharm.ca/document/10427/COVID-19_Booster_Dose_Clarfication_Interval_Revision_20230126.pdf 

  2. Determining COVID-19 Booster Dose Eligibility in Saskatchewan. COVID-19 Vaccine Doses/Eligibility/Intervals [Internet]. medSask; 2023 [updated 2023 Jan 30; cited 2023 Jan 31]. Available from: https://medsask.usask.ca/documents/covid-documents/winter-booster-eligiblity.pdf 
  3. eHealth Saskatchewan. Saskatchewan Immunization Manual. Government of Saskatchewan. [updated 2023 Jan; cited 17 Jan 2023] Available at https://www.ehealthsask.ca/services/manuals/Pages/SIM.aspx  

  4. Government of Saskatchewan. Vaccine Delivery Phases [Internet]. Saskatchewan: Government of Saskatchewan; Publication 2023 [cited 2023 Jan 17]. Available from: https://www.saskatchewan.ca/government/health-care-administration-and-provider-resources/treatment-procedures-and-guidelines/emerging-public-health-issues/2019-novel-coronavirus/covid-19-vaccine/vaccine-delivery-phases 
  5. medSask. Drug Shortages and Discontinuations [Internet]. Saskatoon, SK; 2022 [cited 2023 Jan 9]. Available from: https://medsask.usask.ca/professional-practice/drug-shortages.php 
  6. Bell C, Nijaar G. Injectable and Oral Testosterone Shortage. Drug Shortages and Discontinuations [Internet]. medSask; 2012 [updated 2023 Jan; cited 2023 Jan 26]. Available from: https://medsask.usask.ca/documents/drug-shortages-pdfs/testosterone.pdf 
  7. medSask. Liquid Antibiotic Shortage [Internet]. Saskatoon, SK; 2023 [cited 2023 Jan 12]. Available from: https://medsask-usask-ca.cyber.usask.ca/general-public/liquid-antibiotic-shortage.php 
  8. At Home with Children with Respiratory Infections?. Liquid Antibiotic Shortage [Internet]. medSask; 2022 [cited 2023 Jan 25]. Available from: https://medsask.usask.ca/documents/home-with-sick-children-infographic-dec-22.pdf 
  9. Do Bugs Need Drugs?. Guide to Wise Use of Antibiotics [Internet]. Alberta: Communicable Disease Control Program, Alberta Health Services; 2022 [cited 2023 Jan 13]. Available from: https://dobugsneeddrugs.org/guide-to-wise-use-of-antibiotics/ 

  10. What are Biosimilars? [image]. medSask; 2023 [cited 2023 Jan 26]. 

  11. Travel Health Services and Vaccine-Preventable Diseases FAQ. Saskatchewan College of Pharmacy Professionals; 2021 Sept 28 [cited 2023 Jan 9]. Available from: https://saskpharm.ca/document/5581/REF_Travel_Health_FAQs.pdf 
  12. National Association of Pharmacy Regulatory Authorities (NAPRA) [Internet]. National Drug Schedules. Ontario, ON: NAPRA; 1996. Available from: https://www.napra.ca/national-drug-schedules/medSask
  13. Vaccine Preventable Disease and Travel Health [Internet]. Saskatoon, SK; 2021 [cited 2023 Jan 9]. Available from: https://medsask.usask.ca/professional-practice/restricted-guidelines/vaccine-preventable-disease-and-travel-health.php 
  14. Disease Prevention and Travel Health Services Policy and Framework for Saskatchewan Pharmacists. Saskatchewan College of Pharmacy Professionals; 2021 April 29 [cited 2023 Jan 9]. Available from: https://saskpharm.ca/document/5410/REF_Travel_Health_Disease_Prevention_Travel_Health_Services_Frmwk.pdf 
  15. Public Health Agency of Canada. Cholera and enterotoxigenic escherichia coli (ETEC) travellers' diarrhea vaccine: Canadian Immunization Guide. Ottawa: Government of Canada; [updated 2017 April; cited 2023 Jan 9]. Available from: https://www.canada.ca/en/public-health/services/publications/healthy-living/canadian-immunization-guide-part-4-active-vaccines/page-3-cholera-enterotoxigenic-escherichia-coli-travellers-diarrhea-vaccine.html 
  16. Pharmacy FAQs #2 on Paxlovid™. Saskatchewan Drug Plan [Internet]. COVID-19 Immunization Manual, Government of Saskatchewan; 2022 [cited 2023 Jan 10]. Available from: https://formulary.drugplan.ehealthsask.ca/PDFs/Pharmacy%20FAQs%202%20-%20Paxlovid.pdf 
  17. Bell C. Hepatitis A and Hepatitis B Vaccines: Recommendations for Interrupted Schedules, Booster Doses, Repeat Doses, & Last Minute Travellers. Drug Shortages and Discontinuations [Internet]. medSask; 2020 [updated 2022 Nov; cited 2023 Jan 10]. Available from: https://medsask.usask.ca/documents/mednews-docs/hepatitis_vaccines.pdf 
  18. Public Health Agency of Canada. Hepatitis A vaccine: Canadian Immunization Guide. Ottawa: Government of Canada; [updated 2018 March; cited 12 Jan 2023]. Available from https://www.canada.ca/en/public-health/services/publications/healthy-living/canadian-immunization-guide-part-4-active-vaccines/page-6-hepatitis-a-vaccine.html#p4c5t2 
  19. Immunize.org  [Internet]. Saint Paul, MN: Immunize.org. Hepatitis A; 2021 Dec 10 [cited 2023 Jan 12]. Available from: https://www.immunize.org/askexperts/experts_hepa.asp 
  20. Skokovic-Sunjic D. Clinical Guide to Probiotic Products Available in Canada [Internet]. AEProbio; 2023 [updated 2023 Jan; cited 2023 Jan 13]. Available from: https://probioticchart.ca/PBCIntroduction.html?utm_source=intro_pg&utm_medium=civ&utm_campaign=CDN_CHART 

Newsletters from 2022

December 22, 2022: Biosimilars and Drug Shortages

Read Now

https://mailchi.mp/usask.ca/medsask-newsletter-december-22-2022?e=[UNIQID]

Summary/Highlights
  • The medSask newsletter is now posted on our website.
  • Drug shortage updates: spironolactone, Estrogel® and antibiotic suspensions
  • COVID-19 fall/winter booster program: updates to eligibility based on date of last dose
  • Saskatchewan Biosimilars Initiative: biosimilar bookmarks
  • Influenza prescribing guidelines: 8 minute video summarizing key points for antiviral prescribing
  • From the medSask database
    • Carmen’s Resource Share: LactMed
    • Holiday hours
  • Share your feedback with medSask! Help us create a valuable newsletter each month by completing a short (2-minute) survey.
References
  1. medSask. medSask newsletter [Internet]. Saskatoon, SK; 2022 [cited 2022 Dec 15]. Available from: https://medsask.usask.ca/professional-practice/medsask-newsletter.php#RecentEditions
  2. medSask. Drug Shortages and Discontinuations [Internet]. Saskatoon, SK; 2022 [cited 2022 Dec 15]. Available from: https://medsask.usask.ca/professional-practice/drug-shortages.php
  3. Grindrod K, Barrett B, Killeen R. How to rethink Antibiotic Prescriptions. Pharmacy5in5. [Internet]. University of Waterloo; 2019 [2022 Dec 16]. Available from: https://uwaterloo.ca/pharmacy/sites/ca.pharmacy/files/uploads/files/ams-clinician-infographic_0.pdf
  4. eHealth Saskatchewan. Biologic Products. Saskatchewan Immunization Manual. Government of Saskatchewan. [updated 2022 Dec; cited 15 Dec 2022] Available from: https://www.ehealthsask.ca/services/Manuals/Documents/sim-chapter10.pdf
  5. Health Canada [Internet]. Ottawa, ON: Government of Canada. Biosimilar biologic drugs in Canada: Fact Sheet; 2019 [cited 2022 Dec 19]; [10 pages]. Available from: https://www.canada.ca/en/health-canada/services/drugs-health-products/biologics-radiopharmaceuticals-genetic-therapies/applications-submissions/guidance-documents/fact-sheet-biosimilars.html
  6. Biosimilar Drugs: Your Questions Answered. [Internet]. Canada’s Drug and Health Technology Agency; 2021 April [cited 2022 Dec 15]. Available https://www.cadth.ca/sites/default/files/pdf/biosimilar_drugs_patient_tool.pdf
  7. CDHFtube. IBD: Switching from a Biologic to a Biosimilar [video file]. 2021 March [cited 2022 Dec 15]. Available from: https://cdhf.ca/en/switching-from-a-biologic-to-a-biosimilar/
  8. Arthritis Society Canada [Internet]. Toronto, ON: Arthritis Society Canada; 2022. Biologics and Biosimilars for the Treatment of Inflammatory Arthritis; [cited 2022 Dec 15]; [11 pages]. Available from: https://arthritis.ca/treatment/medication/biologics-and-biosimilars
  9. Arthritis Research Canada. Biosimilars: What You Need to Know [video file]. 2021 May [cited 2022 Dec 19]. Available from: https://www.youtube.com/watch?v=TsK15BzXZEI
  10. Mertens C, Rothblatt Z. Breaking Down Biosimilars [Internet]. Upper Nyack, NY: Global Health Living Foundation; 2021-2022 [cited 2022 Dec 19]. Available from: https://ghlf.org/breaking-down-biosimilars/
  11. medSask. Influenza Minor Ailments Prescribing Guidelines [video file]. 21 Dec 2022. Accessed 22 Dec 2022. Available from: https://us06web.zoom.us/rec/play/CmYnoabl9MNm5k0oPEx530ODzVMJtSZVF9u67cJnzaRLLv7-5EpRkd9MzYj6PiPw8GuRfB91c-Grsffp.TTRvvhuyVUYAA5Ls?continueMode=true&_x_zm_rtaid=q3_7n1sZS4unVKdbEzcXLg.1671737322584.894243c5111446a86529fe36d2903238&_x_zm_rhtaid=274
  12. Toxnet Toxicology Data Network.  Drugs and lactation database (LactMed) [homepage on the Internet].  Bethesda, MD: U.S. National Library of Medicine; 2016- [cited 2022 Dec 15].  Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/

December 9th, 2022: medSask Special Edition: Influenza

Read Now

https://mailchi.mp/usask.ca/medsask-special-edition-influenza?e=[UNIQID]

Summary/Highlights
  • Oseltamivir Availability: update on supply and alternative administration
  • Managing influenza symptoms at home 
  • Co-infection: COVID-19? Influenza? or Both?
  • How to use the Relenza (zanamivir) Diskhaler
  • Key Points & Highlights from the Influenza Minor Ailment Guidelines
References

Influenza Newsletter – special edition. References are recorded in the order in which they appear. 

  1. medSask. Influenza minor ailment guidelines. [Internet]. Saskatoon, SK; [updated Nov 2022; cited 6 Dec 2022]. Available from: https://medsask.usask.ca/professional-practice/restricted-guidelines/influenza.php
  2. Bareham J, Regier L, Kosar L, et al. Medication Administration Challenges in Older Adults: To Crush or Not to Crush List. Geri-RxFiles. 3rd ed. Saskatoon, SK: University of Saskatchewan; 2019. p. 181-191.
  3. CPS [Internet]. Ottawa (ON): Canadian Pharmacists Association; c2021 [updated 2020 Feb 7; cited 2022 Dec 6]. Tamiflu [product monograph]. Available from: http://www.e-cps.ca or https://pdf.hres.ca/dpd_pm/00067405.PDF
  4. At Home with COVID-19 or Influenza? [Internet].  medSask; 28 Nov 2022 [6 Dec 2022]. Available from: https://medsask.usask.ca/documents/covid-documents/managing-covid-19-flu-at-home.pdf
  5. CPS [Internet]. Ottawa (ON): Canadian Pharmacists Association; c2021 [cited 2022 Dec 6]. Available from: http://www.e-cps.ca or http://www.myrxtx.ca. Also available in paper copy from the publisher.
  6. DynaMed [Internet]. Ipswich (MA): EBSCO Publishing. 1995 – 2012.[cited 2022 Dec 6]. Available from http://www.ebscohost.com/dynamed/. Registration and login required.
  7. Up to Date [Internet]. Wolters Kluwer N.V. 2022. [cited 2022 Dec 6]. Available from: https://www.uptodate.com. Subscription required.
  8. Playforth K. The Pediatrician Mom blog [Internet] Virginia: The Pediatrician Mom. 2022. [cited 2022 Dec 6]. Available from: https://www.thepediatricianmom.com/blog
  9. Centers for Disease Control and Prevention [Internet]. Atlanta, GA. Similarities and Differences between Flu and COVID-19; 2022 Sept 28 [cited 2022 Dec 6]; [6 pages]. Available from: https://www.cdc.gov/flu/symptoms/flu-vs-covid19.htm#print
  10. Relenza Prescribing Information. GSK Products [Internet]. GlaxoSmithKline; 2008 [updated 2021 October; cited 2022 Dec 6]. Available from: https://gskpro.com/content/dam/global/hcpportal/en_US/Prescribing_Information/Relenza/pdf/RELENZA-PI-PIL-IFU.PDF
  11. CPS [Internet]. Ottawa (ON): Canadian Pharmacists Association; c2021 [updated 2018 July 20; cited 2022 Dec 6]. Relenza [product monograph]. Available from: http://www.e-cps.ca or  https://pdf.hres.ca/dpd_pm/00046474.PDF
  12. Medicines Org Uk. How to use your diskhaler [video file]. 2010 [cited 2022 Dec 6]. Available from: https://www.youtube.com/watch?v=wak2lw_4GjM
  13. Influenza Q & A [internet]. Immunize Canada; 2022 [cited 2022 Dec 6]. Available from: https://immunize.ca/sites/default/files/Resource%20and%20Product%20Uploads%20(PDFs)/Campaigns/Influenza/2022-2023/influenza_q_and_a_2022_web_e.pdf

November 30th, 2022: Drug Shortages and Biosimilars

Read Now

https://mailchi.mp/usask.ca/medsask-newsletter-november-30th

Summary/Highlights

This edition of the newsletter covers the following content:

  • Professional Practice
    • medSask drug shortage resources: amoxicillin, propranolol, Twinrix®Jr. and spironolactone
    • Using adult pain and fever medication in children and adolescents
    • Paxlovid™ expiry extension - UPDATED infographic to communicate adjusted expiry
  • The Saskatchewan Biosimilars Initiative
  • From the medSask database
    • Ozempic® for weight loss?
    • Kerrie’s Resource Share: Canadian Immunization Guide (CIG)
  • Share your feedback with us! Help us create a valuable newsletter each month by completing a short survey. 

October 28th, 2022: Acetaminophen Shortage and Paxlovid

Read Now

https://mailchi.mp/usask.ca/medsask-newsletter-october-28-2022

Summary/Highlights

This edition of the newsletter covers the following content:

  • Bivalent COVID-19 vaccines currently available in Saskatchewan 
    • Assessing for bivalent vaccine eligibility & confirming valid primary series 
  • Options for influenza vaccine in 65+
  • The Saskatchewan Biosimilars Initiative 
  • Updating your Paxlovid™ prescribing/dispensing status with DPEBB
  • Providing FREE take home naloxone kits within your pharmacy or practice site
  • Acetaminophen Shortage Infographic QR Code Update 
  • Translation services for medSask callers 
  • From the medSask database 
    • Changes to Prevnar®13 availability – Update
    • Dorothy's resource share: Canadian ADHD Practice Guidelines

October 17th, 2022: Special Edition on Acetaminophen Shortage

Read Now

https://mailchi.mp/usask.ca/acetaminophen-shortage-tools-for-pharmacists

Summary/Highlights

This is a special edition of the medSask newsletter highlighting the Acetaminophen shortage and what pharmacists can and cannot do to manage the shortage. This edition of the newsletter covers the following content:

  • Can pharmacists provide compounded acetaminophen suspension?
  • Signage for your pharmacy (education for the general public)
  • Offering alternatives to acetaminophen
  • Key information about prescribing, compounding, and dispensing acetaminophen suspension.

September 29th, 2022: Spikevax™ and Influenza Resources

Read Now

https://mailchi.mp/usask.ca/medsask-newsletter-september-29-2022

Summary/Highlights

This edition of the newsletter covers the following content:

  • Moderna Spikevax™ Bivalent as a booster dose in Saskatchewan
  • Optimizing a vaccination appointment: giving COVID-19 booster dose with influenza vaccine 
  • Influenza immunization resources
  • Navigating the acetaminophen shortage 
  • From the medSask database: Prevnar 20™ and doxepin for itch 
 
No part of this work may be reproduced, distributed, or transmitted in any form or by any means, including photocopying, recording, or other electronic or mechanical methods, without the prior written permission of the copyright holder. For copyright permission requests, please contact druginfo@usask.ca.